Scientific Evidence

Made in Switzerland. Meant for the world.

TIREX® technology is the result of Swiss scientific research and has been tested and validated in two trials as well as in hundreds of individual cases across Europe. These studies were conducted to identify relevant biomarkers and interpret their values while monitoring psychomotor vigilance, reaction speed, performance, driving ability, and subjective perception of fatigue.
To date, TIREX® is backed by five scientific publications with many more underway.

SCIENTIFIC PUBLICATIONS

Leveraging the Metabolic Fingerprint of Sleep Deprivation and Sleep Restriction for Forensic Applications: A Machine Learning Study in Oral Fluid Metabolomics

J. Proteome Research
published May 2026

Effects of Sleep Restriction and Sleep Deprivation on Behaviorally Relevant Electrophysiological Signal Patterns Revealed by Interpretable Machine Learning

SSRN
published March 2026

Effects of acute or cumulative 8-hour sleep loss on simulated driving in a naturalistic, monotonous night-time setting: a randomized, controlled, crossover trial

medRxiv
published Jan 2026

Assessing the influence of sleep and sampling time on metabolites in oral fluid: implications for metabolomics studies

Metabolomics
published Aug 2024

Metabolomics-based Sleepiness Markers for Risk Prevention and Traffic Safety (ME-SMART): a monocentric, controlled, randomized, crossover trial

Trials
published Feb 2023

...and even more coming soon!


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OFFICIAL TRIALS

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